华中农业大学食品生物技术与安全实验室导师信息介绍：李锦铨

代表性论文

1. Genotypic Analyses and Virulence Characterization of Listeria monocytogenes Isolates from Crayfish (Procambarus clarkii) CURRENT MICROBIOLOGY 2015.04

2. Evaluation of the immunogenicity and the protective efficacy of a novel identified immunogenic protein, SsPepO, of Streptococcus suis serotype 2 VACCINE 2011.01

3. The two-component regulatory system CiaRH contributes to the virulence of Streptococcus suis 2 VETERINARY MICROBIOLOGY 2011.01

科研项目 

1. 31772083噬菌体多糖解聚酶介导的肠炎沙门氏菌生物被膜消除机制 2018.01

2. 江苏省人兽共患病学重点实验室 开放课题 2016.07

3. 猪链球菌2型内皮素转化酶的致病机制研究 2016.01

4. 二聚体化影响黄曲霉毒素单链抗体结合能力的机理研究 2016.01

5. 湖北地区小龙虾中副溶血弧菌污染状况和污染机制研究 2015.01

6. 肠炎和伤寒沙门氏菌噬菌体的筛选和初步应用 2014.06

7. 蔬菜内化污染病原菌的分离、分子分型与检测控制技术研究 2014.01

8. 猪链球菌2 型 CiaRH 双组份系统致病机制研究 2013.09 
 
发表论文

(1) Xingxing Dong, Zhi Li, Xiaohong Wang, Min Zhou, Li Lin, Yang Zhou, Jinquan Li*. Characteristics of Vibrio parahaemolyticus isolates obtained from crayfish (Procambarus clarkii) in freshwater. International Journal of Food Microbiology, 2016 Dec 5;238:132-138. doi: 10.1016/j.ijfoodmicro.2016.09.004. (IF=3.4, JCR一区)

(2) Yang Zhou, Xingxing Dong, Zhiwei Li, Geng Zou, Li Lin, Xiaohong Wang, Huanchun Chen, Robin B. Gasser, Jinquan Li*. Predominance of Streptococcus suis ST1 and ST7 in human cases in China, and detection of a novel sequence type, ST658. Virulence. 2016 Sep 30:1-5. (IF=5.4, JCR一区)

(3) Xingxing Dong, Xiaohong Wang, Xingchun Chen, Zhiyun Yan, Jing Cheng, Liangliang Gao, Yuan Liu, Jinquan Li*. Genetic Diversity and Virulence Potential of Staphylococcus aureus Isolated from Crayfish (Procambarus clarkii). Curr Microbiol. 2016 Oct 19. DOI: 10.1007/s00284-016-1147-0.

(4) Jinquan Li, Guanghui Liu,Wenchao Feng,Yang Zhou, Mengyao Liu, James A. Wileya and Benfang Lei*. Neutrophils Select Hypervirulent CovRS Mutants of M1T1 Group A Streptococcus during Subcutaneous Infection of Mice. Infect. Immun, 2014 Apr;82(4):1579-90. doi: 10.1128/IAI.01458-13. (IF=4.1, JCR一区)

(5) Chengkun Zheng, Jiali Xu, Sujing Ren, Jinquan Li, Miaomiao Xia, Huanchun Chen, Weicheng Bei*Identification and characterization of the chromosomal yefM-yoeB toxin-antitoxin system of Streptococcus suis. Sci Rep. 2015 Aug 14; 5: 13125. doi: 10.1038/srep13125. (IF=5.2, JCR一区)

(6) Chengkun Zheng, Sujing Ren, Jiali Xu, Xigong Zhao, Guolin Shi, Jianping Wu, Jinquan Li, Huanchun Chen, Weicheng Bei. Contribution of NADH oxidase to oxidative stress tolerance and virulence of Streptococcus suis serotype 2. Virulence. 2016 Jun 17:1-13. (IF=5.4, JCR一区)

(7) Chengkun Zheng, Jiali Xu, Jinquan Li, Luohong Hu, Jiandong Xia, Jingyan Fan, Weina Guo, Huanchun Chen, Weicheng Bei*. Two Spx Regulators Modulate Stress Tolerance and Virulence in Streptococcus suis Serotype 2. PLoS One. 2014 Sep 29; 9(9): e108197. doi: 10.1371/journal.pone.0108197. eCollection 2014.

(8) Weifeng Chen, Li Hu, Aiping Liu, Jinquan Li, Fusheng Chen, Xiaohong Wang. Expression and characterization of single-chain variable fragment antibody against staphylococcal enterotoxin A in Escherichia coli. Can J Microbiol. 2014 Sep 18:1-7. [Epub ahead of print]

(9) Jinquan Li, Hui Zhu, Wenchao Feng, Mengyao Liu, Yingli Song, Xiaolan Zhang, Yang Zhou, Weicheng Bei, Benfang Lei*. Regulation of Inhibition of Neutrophil Infiltration by Two-Component Regulatory System CovRS in Subcutaneous Mouse Infection with Group A Streptococcus. Infect. Immun, 2013, 81(3): 974-983. (IF=4.1, JCR一区)

(10) Yang Zhou, Tracey S Hanks, Wenchao Feng, Jinquan Li, Guanghui Liu, Mengyao Liu, Benfang Lei*. The sagA/pel locus does not regulate the expression of the M protein of the M1T1 lineage of group A Streptococcus. Virulence. 2013 Nov 15; 4(8): 698-706. doi: 10.4161/viru.26413. Epub 2013 Oct 11. (IF=5.4, JCR一区)

(11) Jinquan Li, Jin Xia, Chen Tan, Yang Zhou, Yang Wang, Chengkun Zheng, Huanchun Chen, Weicheng Bei*. Evaluation of the immunogenicity and the protective efficacy of a novel identified immunogenicprotein, SsPepO, of Streptococcus suis serotype 2. Vaccine, 2011, 29(38):6514-6519. (Top期刊)

(12) Jinquan Li, Chen Tan, Yang Zhou, Shulin Fu, Linlin Hu, Jin Hu, Huanchun Chen, Weicheng Bei*.The two-component regulatory system CiaRH contributes to the virulence of Streptococcus suis 2.Vet. Microbiol, 2011, 148(1):99-104. (JCR一区)

(13) Mengyao Liu, Hui Zhu, Jinquan Li, Cristiana C. Garcia, Wenchao Feng, Liliya N. Kirpotina, Jonathan Hilmer, Luciana P. Tavares, Arthur W. Layton, Mark T. Quinn, Brian Bothner, Mauro M. Teixeira, Benfang Lei*. Group A Streptococcus Secreted Esterase Hydrolyzes Platelet-Activating Factor to Impede Neutrophil Recruitment and Facilitate Innate Immune Evasion. PLoS Pathog, 2012; 8(4): e1002624. (IF=8, Top期刊)

(14) Jinlin Liu, Chen Tan, Jinquan Li, Huiwen Chen, Peng Xu, Qigai He, Weicheng Bei*, Huanchun Chen. Characterization of ISApl1, an insertion element identified from Actinobacillus pleuropneumoniae field isolate in China. Vet. Microbiol, 2008, 132(3-4): 348-354. (Top期刊)

(15) Chen Tan, Manli Liu, Jinquan Li, Meilin Jin, Weicheng Bei*, Huanchun Chen.SsPepcontributes to the virulence of Streptococcussuis. Microb. Pathog,2011, 51(5): 319-324.

(16) Fangyan Yuan, Shulin Fu, Jin Hu, Jinquan Li, Haitao Chang, Linlin Hu, Huanchun Chen, Yongxiang Tian*, Weicheng Bei*. Evaluation of recombinant proteins of Haemophilus parasuis strain SH0165as vaccine candidates in a mouse model. Res Vet Sci, 2012, 93(1): 51-56.

(17) Xinghong Yang*, Theresa Thornburg, Zhiyong Suo, SangMu Jun, Amanda Robison, Jinquan Li, Timothy Lim, Ling Cao, Teri Hoyt, Recep Avci, David W. Pascual. Flagella Overexpression Attenuates Salmonella Pathogenesis. PLoS One, 2012, 7(10): e46828.