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汤朝晖
单位:中国科学院长春应用化学研究所生态环境高分子材料重点实验室
地址:吉林省长春市人民大街5625号
邮编:130022
电话:0431-85262116
个人简历 Personalresume
汤朝晖博士研究员
工作单位:中国科学院长春应用化学研究所,生态环境高分子材料重点实验室
学习经历
1999–2005中国科学院长春应用化学研究所,高分子化学与物理专业,理学博士,导师:陈学思研究员;
1995–1999湘潭大学化学系,理学学士;
工作经历
2015–研究员,中国科学院长春应用化学研究所;
2009–2014副研究员,中国科学院长春应用化学研究所;
2007–2008博士后,美国纽约州立大学石溪分校(StateUniversityofNewYorkatStonyBrook),合作导师:朱鹏年(BenjaminChu),萧守道(BenjaminS.Hsiao);
2005–2006研究助理,英国帝国理工学院(ImperialCollegeLondon),合作导师:VCGibson。
研究兴趣
生物医用高分子材料,药物缓控释
学术论文与专利情况
发表SCI研究论文80余篇,包括ProgressinPolymerScience,ChemicalScience,Biomateials,JournalofControlledRelease等,他引2000余次,授权专利30项。
个人荣誉
1. 2015年入选中国科学院青年创新促进会优秀会员;
2. 2011年入选中国科学院青年创新促进会会员;
3. 汤朝晖,可降解医用高分子材料的基础及应用研究,吉林省科技进步奖,一等奖,排名第7,2011。
4. 汤朝晖,聚乳酸新材料关键技术研发与产业化应用,中国石油与化学工业联合会技术发明奖,一等奖,排名第6,2011。
主持或参加科研项目(课题)
1. 国家自然科学基金面上项目,2016年,高分子纳米化CD47抗体用于恶性肿瘤的研究,62万元,主持;
2. 中国科学院青年创新促进会优秀会员,2015年,优秀会员人才专项经费,150万元,主持;
3. 国家自然科学基金面上项目,51373168,物理化学性质和肿瘤种类对高分子纳米粒子在小鼠体内代谢和分布的影响研究,2014/01–2017/12,80万元,主持;
4. 国家科技重大专项重大新药创制,2014ZX09507-009,IPT-ZHW155的临床前研究,2014/01–2016/12,40.5万元,参加(子课题副组长);
5. 吉林省医药产业发展专项资金项目,20130727050YY,聚谷氨酸接枝聚乙二醇药用辅料及顺铂胶束制剂的研究和开发,2013/06–2016/05,50万元,主持;
6. 国家科技重大专项重大新药创制,2013ZX09J13110-11B,基于生物可降解高分子电纺丝技术的战伤救治药物体系,2013/01–2015/12,110万元参加(子课题副组长);
7. 吉林省科技发展计划项目,科技支撑计划,重点科技攻关项目,20130206066GX,用于抗肿瘤药物靶向控释的高分子载体材料的研究和开发,2013/01–2015/12,18万元,主持;
8. 国家自然科学基金面上项目,51173184,氧化还原和pH双敏感的纳米药物控释系统及其克服肿瘤多药耐药性研究,2012/01–2015/12,65万元,主持;
9. 中国科学院青年创新促进会会员,2011年,会员人才专项经费,40万元,主持;
10. 国家自然科学青年基金,2009年,具有生物分子识别功能可生物降解高分子材料的合成与应用,23万元,主持。
学术论文与书籍章节目录
[1]Y.Zhang,C.Xiao,J.Ding,M.Li,X.Chen,Z.Tang,X.Zhuang,X.Chen,Acomparativestudyoflinear,Y-shapedandlinear-dendriticmethoxypoly(ethyleneglycol)-block-polyamidoamine-block-poly(l-glutamicacid)blockcopolymersfordoxorubicindeliveryinvitroandinvivo,ActaBiomater.40(2016)243-253.
[2]H.Yu,Z.Tang,M.Li,W.Song,D.Zhang,Y.Zhang,Y.Yang,H.Sun,M.Deng,X.Chen,Cisplatinloadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)complexnanoparticlesforpotentialcancertherapy:preparation,invitroandinvivoevaluation,JBiomedNanotechnol.12(1)(2016)69-78.
[3]Y.Wang,S.Lv,M.Deng,Z.Tang,X.Chen,Acharge-conversionalintracellular-activatedpolymericprodrugfortumortherapy,Polym.Chem.7(2016)2253-2263.
[4]Z.Tang,C.He,H.Tian,J.Ding,B.S.Hsiao,B.Chu,X.Chen,Polymericnanostructuredmaterialsforbiomedicalapplications,Prog.Polym.Sci.60(2016)86-128.
[5]W.Song,Z.Tang,D.Zhang,X.Wen,S.Lv,Z.Liu,M.Deng,X.Chen,SolidTumorTherapyUsingaCannonandPawnCombinationStrategy,Theranostics6(7)(2016)1023-1030.
[6]W.Song,Z.Tang,D.Zhang,M.Li,J.Gu,X.Chen,Acooperativepolymericplatformfortumor-targeteddrugdelivery,ChemicalScience7(1)(2016)728-736.
[7]W.Song,Z.Tang,N.Shen,H.Yu,Y.Jia,D.Zhang,J.Jiang,C.He,H.Tian,X.Chen,Combiningdisulfiramandpoly(l-glutamicacid)-cisplatinconjugatesforcombatingcisplatinresistance,J.Control.Release231(2016)94-102.
[8]W.Song,Z.Tang,T.Lei,X.Wen,G.Wang,D.Zhang,M.Deng,X.Tang,X.Chen,StableloadinganddeliveryofdisulfiramwithmPEG-PLGA/PCLmixednanoparticlesfortumortherapy,Nanomed.Nanotechnol.Biol.Med.12(2)(2016)377-86.
[9]Y.Niu,W.Song,D.Zhang,Z.Tang,M.Deng,X.Chen,Functionalcomputer-to-platenear-infraredabsorbersashighlyefficientphotoacousticdyes,ActaBiomater.43(2016)262-8.
[10]C.He,Z.Tang,H.Tian,X.Chen,Co-deliveryofchemotherapeuticsandproteinsforsynergistictherapy,Adv.DrugDel.Rev.98(2016)64-76.
[11]J.Chen,L.Lin,Z.Guo,C.Xu,Y.Li,H.Tian,Z.Tang,C.He,X.Chen,N-IsopropylacrylamideModifiedPolyethyleniminesasEffectivesiRNACarriersforCancerTherapy,JournalofNanoscienceandNanotechnology16(6)(2016)5464-5469.
[12]Z.Ahmad,S.Lv,Z.Tang,A.Shah,X.Chen,Methoxypoly(ethyleneglycol)-block-poly(glutamicacid)-graft-6-(2-nitroimidazole)hexylaminenanoparticlesforpotentialhypoxia-responsivedeliveryofdoxorubicin,J.Biomater.Sci.Polym.Ed.27(1)(2016)40-54.
[13]马丽莉,邵俊,杨晨光,汤朝晖,陈学思,PDLA-PBS-PDLA三嵌段共聚物的合成及性能,高等学校化学学报36(11)(2015)2329-2334.
[14]H.Yu,Z.Tang,D.Zhang,W.Song,Y.Zhang,Y.Yang,Z.Ahmad,X.Chen,Pharmacokinetics,biodistributionandinvivoefficacyofcisplatinloadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)complexnanoparticlesfortumortherapy,J.Control.Release205(2015)89-97.
[15]H.Yu,Z.Tang,D.Zhang,W.Song,T.Duan,J.Gu,X.Chen,Poly(ornithine‐co‐arginine‐co‐glycine‐co‐asparticAcid):PreparationviaNCAPolymerizationanditsPotentialasaPolymericTumor‐PenetratingAgent,Macromol.Biosci.15(6)(2015)829–838.
[16]H.Yu,Z.Tang,W.Song,D.Zhang,Y.Zhang,X.Chen,Co-administrationofiRGDenhancingtheanticancerefficacyofcisplatin-loadedpolypeptidenanoparticles,J.Control.Release213(2015)e145-e146.
[17]H.Y.YifeiLi,HaiSun,JianguoLiu,ZhaohuiTang,DanWang,LianyouYu,XuesiChen,Cisplatin-loadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)nanoparticlesasapotentialchemotherapeuticagentagainstosteosarcoma,Chin.J.Polym.Sci.33(5)(2015)763-771.
[18]W.Song,Z.Tang,D.Zhang,H.Yu,X.Chen,CoadministrationofVascularDisruptingAgentsandNanomedicinestoEradicateTumorsfromPeripheralandCentralRegions,Small11(31)(2015)3755-3761.
[19]W.Song,Z.Tang,D.Zhang,N.Burton,W.Driessen,X.Chen,Comprehensivestudiesofpharmacokineticsandbiodistributionofindocyaninegreenandliposomalindocyaninegreenbymultispectraloptoacoustictomography,RSCAdv.5(5)(2015)3807-3813.
[20]C.Shi,H.Yu,D.Sun,L.Ma,Z.Tang,Q.Xiao,X.Chen,Cisplatin-loadedpolymericnanoparticles:Characterizationandpotentialexploitationforthetreatmentofnon-smallcelllungcarcinoma,ActaBiomater.18(2015)68–76.
[21]M.Q.Li,Z.H.Tang,Y.Zhang,S.X.Lv,Q.S.Li,X.S.Chen,TargeteddeliveryofcisplatinbyLHRH-peptideconjugateddextrannanoparticlessuppressesbreastcancergrowthandmetastasis,ActaBiomater.18(2015)132-143.
[22]M.Li,Z.Tang,D.Zhang,H.Sun,H.Liu,Y.Zhang,Y.Zhang,X.Chen,Doxorubicin-loadedpolysaccharidenanoparticlessuppressthegrowthofmurinecolorectalcarcinomaandinhibitthemetastasisofmurinemammarycarcinomainrodentmodels,Biomaterials51(0)(2015)161-172.
[23]B.Feng,Z.Xu,F.Zhou,H.Yu,Q.Sun,D.Wang,Z.Tang,H.Yu,Q.Yin,Z.Zhang,Y.Li,Nearinfraredlight-actuatedgoldnanorodswithcisplatin-polypeptidewrappingfortargetedtherapyoftriplenegativebreastcancer,Nanoscale7(36)(2015)14854-64.
[24]R.Zhao,X.Li,B.Sun,Y.Zhang,D.Zhang,Z.Tang,X.Chen,C.Wang,Electrospunchitosan/sericincompositenanofiberswithantibacterialpropertyaspotentialwounddressings,Int.J.Biol.Macromol.68(2014)92-97.
[25]H.Yu,Z.Tang,W.Song,M.Deng,X.Chen,CurrentStatusandFutureProspectsofPolymericNanocarrierforTumorTargeting,Chem.J.Chin.Univ.-Chin.35(5)(2014)903-916.
[26]W.Song,Z.Tang,D.Zhang,Y.Zhang,H.Yu,M.Li,S.Lv,H.Sun,M.Deng,X.Chen,Anti-tumorefficacyofc(RGDfK)-decoratedpolypeptide-basedmicellesco-loadedwithdocetaxelandcisplatin,Biomaterials35(9)(2014)3005-3014.
[27]W.Song,Z.Tang,M.Li,S.Lv,H.Sun,M.Deng,H.Liu,X.Chen,Polypeptide-basedcombinationofpaclitaxelandcisplatinforenhancedchemotherapyefficacyandreducedside-effects,ActaBiomater.10(3)(2014)1392-1402.
[28]J.Shao,Z.Tang,J.Sun,G.Li,X.Chen,LinearandFour-ArmedPoly(L-lactide)-block-poly(D-lactide)CopolymersandTheirStereocomplexationwithPoly(lactide)s,JournalofPolymerSciencePartB-PolymerPhysics52(23)(2014)1560-1567.
[29]Z.Qu,R.Duan,X.Pang,B.Gao,X.Li,Z.Tang,X.Wang,X.Chen,LivingandStereoselectivePolymerizationofRac-LactidebyBimetallicAluminumSchiff-BaseComplexes,JournalofPolymerScienceParta-PolymerChemistry52(9)(2014)1344-1352.
[30]S.Lv,Z.Tang,D.Zhang,W.Song,M.Li,J.Lin,H.Liu,X.Chen,Well-definedpolymer-drugconjugateengineeredwithredoxandpH-sensitivereleasemechanismforefficientdeliveryofpaclitaxel,J.Control.Release194(2014)220-227.
[31]S.Lv,Z.Tang,M.Li,J.Lin,W.Song,H.Liu,Y.Huang,Y.Zhang,X.Chen,Co-deliveryofdoxorubicinandpaclitaxelbyPEG-polypeptidenanovehicleforthetreatmentofnon-smallcelllungcancer,Biomaterials35(23)(2014)6118-6129.
[32]S.Lv,W.Song,Z.Tang,M.Li,H.Yu,H.Hong,X.Chen,Charge-ConversionalPEG-PolypeptidePolyionicComplexNanoparticlesfromSimpleBlendingofaPairofOppositelyChargedBlockCopolymersasanIntelligentVehicleforEfficientAntitumorDrugDelivery,Mol.Pharm.11(5)(2014)1562-1574.
[33]Q.Li,S.Lv,Z.Tang,M.Liu,D.Zhang,Y.Yang,X.Chen,Aco-deliverysystembasedonpaclitaxelgraftedmPEG-b-PLGloadedwithdoxorubicin:Preparation,invitroandinvivoevaluation,Int.J.Pharm.471(1–2)(2014)412-420.
[34]M.-q.Li,Z.-h.Tang,C.Wang,Y.Zhang,H.-t.Cui,X.-s.Chen,Efficientside-chainmodificationofdextranviabase-catalyzedepoxidering-openingandthiol-eneclickchemistryinaqueousmedia,Chin.J.Polym.Sci.32(8)(2014)969-974.
[35]M.Li,Z.Tang,Y.Zhang,S.Lv,H.Yu,D.Zhang,H.Hong,X.Chen,LHRH-peptideconjugateddextrannanoparticlesfortargeteddeliveryofcisplatintobreastcancer,J.Mat.Chem.B2(22)(2014)3490-3499.
[36]M.Li,Z.Tang,S.Lv,W.Song,H.Hong,X.Jing,Y.Zhang,X.Chen,CisplatincrosslinkedpH-sensitivenanoparticlesforefficientdelivery.ofdoxorubicin,Biomaterials35(12)(2014)3851-3864.
[37]M.Li,Z.Tang,J.Lin,Y.Zhang,S.Lv,W.Song,Y.Huang,X.Chen,SynergisticAntitumorEffectsofDoxorubicin-LoadedCarboxymethylCelluloseNanoparticleinCombinationwithEndostarforEffectiveTreatmentofNon-Small-CellLungCancer,Adv.Healthc.Mater.3(11)(2014)1877-1888.
[38]Z.Guo,H.Tian,L.Lin,J.Chen,C.He,Z.Tang,X.Chen,HydrophobicPolyalanineModifiedHyperbranchedPolyethylenimineasHighEfficientpDNAandsiRNACarrier,Macromol.Biosci.14(10)(2014)1406-1414.
[39]J.Chen,J.Xia,H.Tian,Z.Tang,C.He,X.Chen,Thermo-/pH-dualresponsivepropertiesofhyperbranchedpolyethyleniminegraftedbyphenylalanine,Arch.Pharm.Res.37(1)(2014)142-148.
[40]Z.Ahmad,Z.Tang,A.Shah,S.Lv,D.Zhang,Y.Zhang,X.Chen,CisplatinLoadedMethoxyPoly(ethyleneglycol)-block-Poly(L-glutamicacid-co-L-Phenylalanine)NanoparticlesagainstHumanBreastCancerCell,Macromol.Biosci.14(9)(2014)1337-1345.
[41]L.Zhao,C.Xiao,J.Ding,P.He,Z.Tang,X.Pang,X.Zhuang,X.Chen,Facileone-potsynthesisofglucose-sensitivenanogelviathiol-eneclickchemistryforself-regulateddrugdelivery,ActaBiomater.9(5)(2013)6535-6543.
[42]L.Zhao,J.Ding,C.Xiao,P.He,Z.Tang,X.Chen,Phenylboronicacidfunctionalizedpolypeptidemicellesforglucose-responsiveinsulinreleaseatphysiologicalpH,J.Control.Release172(1)(2013)E110-E110.
[43]S.Lv,M.Li,Z.Tang,W.Song,H.Sun,H.Liu,X.Chen,Doxorubicin-loadedamphiphilicpolypeptide-basednanoparticlesasanefficientdrugdeliverysystemforcancertherapy,ActaBiomater.9(12)(2013)9330-9342.
[44]M.Li,Z.Tang,H.Sun,J.Ding,W.Song,X.Chen,pHandreductiondual-responsivenanogelcross-linkedbyquaternizationreactionforenhancedcellularinternalizationandintracellulardrugdelivery,Polym.Chem.4(4)(2013)1199-1207.
[45]M.Li,W.Song,Z.Tang,S.Lv,L.Lin,H.Sun,Q.Li,Y.Yang,H.Hong,X.Chen,NanoscaledPoly(L-glutamicacid)/Doxorubicin-AmphiphileComplexaspH-responsiveDrugDeliverySystemforEffectiveTreatmentofNonsmallCellLungCancer,AcsAppliedMaterials&Interfaces5(5)(2013)1781-1792.
[46]M.Li,S.Lv,Z.Tang,W.Song,H.Yu,H.Sun,H.Liu,X.Chen,Polypeptide/DoxorubicinHydrochloridePolymersomesPreparedThroughOrganicSolvent-freeTechniqueasaSmartDrugDeliveryPlatform,Macromol.Biosci.13(9)(2013)1150-1162.
[47]D.Li,H.Sun,J.Ding,Z.Tang,Y.Zhang,W.Xu,X.Zhuang,X.Chen,Polymerictopologyandcompositionconstrainedpolyether-polyestermicellesfordirectionalantitumordrugdelivery,ActaBiomater.9(11)(2013)8875-8884.
[48]Y.Huang,Z.Tang,X.Zhang,H.Yu,H.Sun,X.Pang,X.Chen,pH-TriggeredCharge-ReversalPolypeptideNanoparticlesforCisplatinDelivery:PreparationandInVitroEvaluation,Biomacromolecules14(6)(2013)2023-2032.
[49]P.He,C.-w.Zhao,C.-s.Xiao,Z.-h.Tang,X.-s.Chen,Thermosensitivepolyioncomplexmicellespreparedbyself-assemblyoftwooppositelychargeddiblockcopolymers,Chin.J.Polym.Sci.31(2)(2013)318-324.
[50]P.He,H.Liu,Z.Tang,M.Deng,Y.Yang,X.Pang,X.Chen,Poly(esteramide)blendmicrospheresfororalinsulindelivery,Int.J.Pharm.455(1-2)(2013)259-266.
[51]C.He,Z.Tang,H.Tian,X.Chen,ProgressintheDevelopmentofBiomedicalPolymerMaterialsFabricatedby3-DimensionalPrintingTechnology,ActaPolymericaSinica(6)(2013)722-732.
[52]J.Guo,X.Li,H.Yu,Z.Tang,X.Tang,C.Cai,J.Xu,H.Xu,Theanti-melanomaefficiencyoftheintratumoralinjectionofcucurbitacin-loadedsustained-releasecarriers:APLGAparticlesystem,J.Pharm.Sci.102(8)(2013)2550-2563.
[53]B.Gao,R.Duan,X.Pang,X.Li,Z.Qu,Z.Tang,X.Zhuang,X.Chen,StereoselectiveRing-OpeningPolymerizationofrac-LactidesCatalyzedbyAluminumHemi-SalenComplexes,Organometallics32(19)(2013)5435-5444.
[54]L.Zhao,J.Ding,C.Xiao,P.He,Z.Tang,X.Pang,X.Zhuang,X.Chen,Glucose-sensitivepolypeptidemicellesforself-regulatedinsulinreleaseatphysiologicalpH,J.Mater.Chem.22(24)(2012)12319-12328.
[55]H.Tian,Z.Tang,X.Zhuang,X.Chen,X.Jing,Biodegradablesyntheticpolymers:Preparation,functionalizationandbiomedicalapplication,Prog.Polym.Sci.37(2)(2012)237-280.
[56]W.Song,C.Xiao,L.Cui,Z.Tang,X.Zhuang,X.Chen,FacileconstructionoffunctionalbiosurfaceviaSI-ATRPand"clickglycosylation",ColloidSurf.B-Biointerfaces93(2012)188-194.
[57]W.Song,Z.Tang,M.Li,S.Lv,H.Yu,L.Ma,X.Zhuang,Y.Huang,X.Chen,TunablepH-SensitivePoly(beta-aminoester)sSynthesizedfromPrimaryAminesandDiacrylatesforIntracellularDrugDelivery,Macromol.Biosci.12(10)(2012)1375-1383.
[58]W.Song,M.Li,Z.Tang,Q.Li,Y.Yang,H.Liu,T.Duan,H.Hong,X.Chen,Methoxypoly(ethyleneglycol)-block-Poly(L-glutamicacid)-LoadedCisplatinandaCombinationWithiRGDfortheTreatmentofNon-Small-CellLungCancers,Macromol.Biosci.12(11)(2012)1514-1523.
[59]D.Li,J.X.Ding,Z.H.Tang,H.Sun,X.L.Zhuang,J.Z.Xu,X.S.Chen,InvitroevaluationofanticancernanomedicinesbasedondoxorubicinandamphiphilicY-shapedcopolymers,Int.J.Nanomedicine7(2012)2687-2697.
[60]P.He,Z.Tang,L.Lin,M.Deng,X.Pang,X.Zhuang,X.Chen,NovelBiodegradableandpH-SensitivePoly(esteramide)MicrospheresforOralInsulinDelivery,Macromol.Biosci.12(4)(2012)547-556.
[61]C.He,X.Zhuang,Z.Tang,H.Tian,X.Chen,Stimuli-SensitiveSyntheticPolypeptide-BasedMaterialsforDrugandGeneDelivery,Adv.Healthc.Mater.1(1)(2012)48-78.
[62]汤朝晖,陈学思,新型药控/缓释材料,中国新材料产业发展报告(2010)2011.
[63]X.-l.Zhuang,H.-y.Yu,Z.-h.Tang,K.Oyaizu,H.Nishide,X.-s.Chen,PolymerizationoflacticO-carboxylicanhydrideusingorganometalliccatalysts,Chin.J.Polym.Sci.29(2)(2011)197-202.
[64]L.Zhao,J.Ding,P.He,C.Xiao,Z.Tang,X.Zhuang,X.Chen,AnefficientpHsensitiveoralinsulindeliverysystemenhancedbydeoxycholicacid,J.Control.Release152(2011)E184-E186.
[65]W.Wang,J.Ding,C.Xiao,Z.Tang,D.Li,J.Chen,X.Zhuang,X.Chen,SynthesisofAmphiphilicAlternatingPolyesterswithOligo(ethyleneglycol)SideChainsandPotentialUseforSustainedReleaseDrugDelivery,Biomacromolecules12(7)(2011)2466-2474.
[66]J.Ding,X.Zhuang,C.Xiao,Y.Cheng,L.Zhao,C.He,Z.Tang,X.Chen,Preparationofphoto-cross-linkedpH-responsivepolypeptidenanogelsaspotentialcarriersforcontrolleddrugdelivery,J.Mater.Chem.21(30)(2011)11383-11391.
[67]J.Ding,C.Xiao,L.Zhao,Y.Cheng,L.Ma,Z.Tang,X.Zhuang,X.Chen,Poly(L-glutamicacid)GraftedwithOligo(2-(2-(2-methoxyethoxy)ethoxy)ethylmethacrylate):ThermalPhaseTransition,SecondaryStructure,andSelf-Assembly,JournalofPolymerScienceParta-PolymerChemistry49(12)(2011)2665-2676.
[68]J.Ding,C.Xiao,L.Yan,Z.Tang,X.Zhuang,X.Chen,X.Jing,pHanddualredoxresponsivenanogelbasedonpoly(l-glutamicacid)aspotentialintracellulardrugcarrier,J.Control.Release152(2011)E11-E13.
[69]J.Ding,C.Xiao,Z.Tang,X.Zhuang,X.Chen,HighlyEfficient"GraftingFrom"analpha-HelicalPolypeptideBackbonebyAtomTransferRadicalPolymerization,Macromol.Biosci.11(2)(2011)192-198.
[70]C.Xiao,C.Zhao,P.He,Z.Tang,X.Chen,X.Jing,FacileSynthesisofGlycopolypeptidesbyCombinationofRing-OpeningPolymerizationofanAlkyne-SubstitutedN-carboxyanhydrideandClick"Glycosylation",Macromol.RapidCommun.31(11)(2010)991-997.
[71]F.Wan,Z.Tang,W.He,B.Chu,Achemistry/physicspathwaywithnanofibrousscaffoldsforgenedelivery,PCCP12(39)(2010)12379-12389.
[72]X.Pang,X.Zhuang,Z.Tang,X.Chen,Polylacticacid(PLA):Research,developmentandindustrialization,BiotechnologyJournal5(11)(2010)1125-1136.
[73]Z.H.Tang,C.Q.Qiu,J.R.McCutcheon,K.Yoon,H.Y.Ma,D.F.Fang,E.Lee,C.Kopp,B.S.Hsiao,B.Chu,DesignandFabricationofElectrospunPolyethersulfoneNanofibrousScaffoldforHigh-FluxNanofiltrationMembranes,JournalofPolymerSciencePartB-PolymerPhysics47(22)(2009)2288-2300.
[74]Z.Tang,J.Wei,L.Yung,B.Ji,H.Ma,C.Qiu,K.Yoon,F.Wan,D.Fang,B.S.Hsiao,B.Chu,UV-curedpoly(vinylalcohol)ultrafiltrationnanofibrousmembranebasedonelectrospunnanofiberscaffolds,J.Membr.Sci.328(1-2)(2009)1-5.
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专利目录(部分)
1. 汤朝晖;孙环娇;于海洋;吕世贤;张大为;陈学思一种高分子抗肿瘤前药及其制备方法.CN201410417521.7,2014.
2. 汤朝晖;李明强;于海洋;宋万通;陈学思改性聚多糖及其制备方法.CN201410133893.7,2014.
3. 汤朝晖;李明强;林坚;宋万通;陈学思聚多巴胺纳米粒子的应用.CN201410177537.5,2014.
4. 汤朝晖;李明强;高中辉;于海洋;陈学思一种聚苯胺纳米粒子的制备方法及其应用.CN201410177564.2,2014.
5. 汤朝晖;于海洋;宋万通;李明强;陈学思阿霉素复合物及其制备方法.CN201310002466.0,2013.
6. 汤朝晖;宋万通;于海洋;李明强;陈学思二氯-1,2-环己二胺合铂配合物及其制备方法.CN201310361430.1,2013.
7. 汤朝晖;吕世贤;陈学思;李明强;宋万通;于海洋氨基酸嵌段共聚物及其制备方法和复合物.CN201310009638.7,2013.
8. 汤朝晖;李明强;宋万通;陈学思一种二价双核铂配合物及其制备方法.CN201310361461.7,2013.
9. 汤朝晖;李明强;陈学思;张影乙二胺四乙酸双核铂配合物及其制备方法.CN201310449569.1,2013.
10. 汤朝晖;李雪;于海洋;张大为;宋万通;陈学思一种创伤止血敷料的制备方法.CN201310547279.0,2013.
11. 汤朝晖;李明强;林坚;宋万通;吕世贤;陈学思共担载顺铂和阿霉素的复合物、胶束及胶束的制备方法.CN201310039396.6,2013.
12. 孙海;汤朝晖;许午;高战团;庄秀丽;陈学思一种紫杉醇高分子键合药及其制备方法.CN201310588848.6,2013.
13. 汤朝晖;于海洋;宋万通;李明强;庄秀丽;陈学思顺铂配合物及其制备方法.CN201210382696.X,2012.
14. 汤朝晖;宋万通;吕世贤;于海洋;陈学思一种聚乙二醇-聚β-胺酯嵌段共聚物及其制备方法.CN201210311209.0,2012.
15. 汤朝晖;宋万通;李明强;丁建勋;于海洋;陈学思一种聚氨基酸接枝共聚物及其制备方法.CN201210391089.X,2012.
16. 汤朝晖;李明强;宋万通;吕世贤;陈学思;庄秀丽阿霉素纳米粒及其制备方法.CN201210034414.7,2012.
17. 汤朝晖;李明强;宋万通;丁建勋;陈学思;庄秀丽阿霉素复合物、胶束及胶束的制备方法.CN201210034443.3,2012.
18. 汤朝晖;李明强;宋万通;陈学思;陈杰;庄秀丽顺铂配合物及其制备方法.CN201210034430.6,2012.
19. 汤朝晖;黄月;陈学思一种顺铂配合物及其制备方法.CN201210430624.8,2012.
20. 陈学思;赵丽;肖春生;丁建勋;何盼;汤朝晖聚合物、葡萄糖纳米凝胶、葡萄糖纳米凝胶组合物及其制备方法.CN201210512665.1,2012.
21. 庄秀丽;丁建勋;肖春生;贺超良;汤朝晖;陈学思聚氨基酸接枝共聚物及其制备方法.CN201110023705.1,2011.
22. 庄秀丽;丁建勋;栗迪;汤朝晖;陈学思聚氨基酸嵌段共聚物及其制备方法.CN201110343619.9,2011.
23. 汤朝晖;赵丽;丁建勋;肖春生;何盼;陈学思共聚物、葡萄糖敏感胶束、葡萄糖敏感载药胶束及其制备方法.CN201110260560.7,2011.
24. 汤朝晖;赵丽;丁建勋;何盼;肖春生;庄秀丽;陈学思一种胰岛素载药微球及其制备方法.CN201110023708.5,2011.
25. 汤朝晖;栗迪;丁建勋;孙海;庄秀丽;陈学思嵌段共聚物及其制备方法.CN201110325770.X,2011.
26. 汤朝晖;栗迪;丁建勋;孙海;庄秀丽;陈学思抗肿瘤前药及其制备方法.CN201110149748.4,2011.
27. 陈学思;何盼;汤朝晖;庄秀丽;林琳胰岛素载药微球及其制备方法.CN201110368851.8,2011.
28. 庄秀丽;高晓晔;汤朝晖;陈学思一种聚(L-谷氨酸)/聚丙烯酸水凝胶及其制备方法.CN201010130914.1,2010.
29. 庄秀丽;丁建勋;赵丽;肖春生;汤朝晖;陈学思一种聚合物微凝胶及其制备方法.CN201010130890.X,2010.
30. 庄秀丽;丁建勋;肖春生;成一龙;赵丽;汤朝晖;陈学思聚(L-谷氨酸)均聚物、无规共聚物、接枝共聚物及其制备方法.CN201010563665.5,2010.
31. 庄秀丽;丁建勋;汤朝晖;陈学思一种功能化聚酯及其制备方法.CN201010130905.2,2010.
32. 庄秀丽;丁建勋;汤朝晖;陈学思聚合物纳米水凝胶及其制备方法.CN201010561226.0,2010.
33. 庄秀丽;丁建勋;高晓晔;肖春生;汤朝晖;陈学思聚合物纳米水凝胶及其制备方法.CN201010563357.2,2010.
34. 庄秀丽;丁建勋;肖春生;赵长稳;汤朝晖;陈学思氯乙醇功能化聚(L-谷氨酸)均聚与无规共聚物及制法和应用.CN200910218013.5,2009.
研究方向 Researchdirection
1、生物医用高分子材料
2、药物缓控释高分子载体
3、纳米药物
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