北京市结核病胸部肿瘤研究所

免疫学专业

褚洪迁，男，北京大学医学博士，国家纳米科学中心博士后，现任北京市结核病胸部肿瘤研究所副研究员，硕士研究生导师。

研究方向为基于复合纳米材料的疾病诊疗作用研究。主要是结合肿瘤临床治疗的困境设计合成多功能复合纳米材料，实现时空可控的精准抗肿瘤免疫。先后在Nat Commun、Angew Chem Int Ed Engl、Environ Pollut、Sci Total Environ等国际刊物上发表高水平论文10余篇，参与发表中英文文章30余篇。主持局级以上科研课题3项，其中包括国家自然科学基金1项(在研)，北京市自然科学基金1项(在研)，北京市医院管理中心培育项目1项(在研)，同时参与多项局级以上课题。与天津大学、中央民族大学、国家纳米科学中心一直保持深度合作，整合多平台实现人才有效培养。现为中国研究型医院协会医工转化与健康产业融合分会委员。

论文发表：

1. Jianhong Ge#, Hongqian Chu#, Qianqian Xiao, Weidong Hao, Jing Shang, Tong Zhu, Zhaogang Sun, Xuetao Wei*. BC and 1,4NQ-BC up-regulate the cytokines and enhance IL-33 expression in LPS pretreatment of human bronchial epithelial cells. Environ. Pollut. 2021, 273:116452.

2. Hongqian Chu#, Xi Tao#, Zhaogang Sun, Weidong Hao, Xuetao Wei*. Galactooligosaccharides protects against DSS-induced murine colitis through regulating intestinal flora and inhibiting NF-κB pathway. Life Sci. 2020, 242: 117220.

3. Hongqian Chu, Jian Zhao, Yongsheng Mi, Zhenghan Di, Lele Li*. NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices. Nat. Commun. 2019, 10(1): 2839.

4. Hongqian Chu#, Jian Zhao#, Yongsheng Mi, Yuliang Zhao, Lele Li*. Near-infrared light-initiated hybridization chain reaction for spatially and temporally resolved signal amplification. Angew. Chem. Int. Ed. Engl. 2019, 58(42): 14877-14881.

5. Zhiyuan Cheng#, Hongqian Chu#, Siqi Wang, Yao Huang, Xiaohong Hou, Qi Zhang, Wenjuan Zhou, Lixia Jia, Qinghe Meng, Lanqin Shang, Yiming Song, Weidong Hao, Xuetao Wei*. TAK1 knock-down in macrophage alleviate lung inflammation induced by black carbon and aged black carbon. Environ. Pollut. 2019, 253: 507-515.

6. Hongqian Chu, Weidong Hao, Zhiyuan Cheng, Yao Huang, Siqi Wang, Jing Shang, Xiaohong Hou, Qinghe Meng, Qi Zhang, Lixia Jia, Wenjuan Zhou, Pengmin Wang, Guang Jia, Tong Zhu, Xuetao Wei*. Black Carbon Particles and Ozone-Oxidized Black Carbon Particles Induced Lung Damage in Mice Through an interleukin-33 Dependent Pathway. Sci. Total Environ. 2018, 644: 217-228.

7. Hongqian Chu, Jing Shang, Ming Jin, Yueyue Chen, Yuan Li, Yao Pan, Xi Tao, Zhiyuan Cheng, Qinghe Meng, Qian Li, Guang Jia, Tong Zhu, Xuetao Wei*, Weidong Hao*. Comaprison of lung damage in mice exposed to black carbon particles and 1,4-naphthoquinone coated black carbon particles. Sci. Total Environ. 2017. 580:572-581.

8. Hongqian Chu, Jing Shang, Ming Jin, Qian Li, Yueyue Chen, Hongpeng Huang, Yuan Li, Yao Pan, Xi Tao, Zhiyuan Cheng, Qinghe Meng, Guang Jia, Tong Zhu, Xuetao Wei*, Weidong Hao*. Comaprison of lung damage in mice exposed to black carbon particles and ozone-oxidized black carbon particles. Sci. Total Environ. 2016. 573: 303-312.

9. Hongqian Chu#, Qiuqiong Tang#, Hongpeng Huang, Weidong Hao, Xuetao Wei*. Grape-seed proanthocyanidins inhibit the lipopolysaccharide-induced inflammatory mediator expression in RAW264.7 macrophages by suppressing MAPK and NF-Κb signal pathways. Environ. Toxicol. Pharmacol, 2016. 41: 159-166.

10. Hongqian Chu#, Jun Li#, Hongpeng Huang, Weidong Hao, Liping Duan*, Xuetao Wei*. Protective effects of tranilast on oxazolone-induced rat colitis through a mast cell-dependent pathway. Dig. Liver Dis. 2016. 48: 162-171.